The photomicrographs are from rats with chronic, lifetime, whole body aerosol exposure to a test compound for 6 hours/day, 5 days/week, for 2 years.
The rats were part of a study to assess toxic effects and carcinogenesis mechanisms of inhaled nickel subsulfide (Ni3S2).
Treated with a test compound administered subcutaneously daily for 46 days.
4-week gavage safety study with a test compound.
6 month carcinogenicity study.