Environmental Impacts on Neurodevelopmental and Neurodegenerative Conditions
Friday, September 11, 2026 |12:00 Noon–3:45 PM EDT
Co-Chairs: Debra Tokarz, DVM, PhD, DACVP, Genentech; and Ramesh Kovi, BVSc & AH, MVSc, PhD, DACVP, DABT, FIATP, Alnylam Pharmaceuticals Inc
Environmental exposures can negatively impact the developing nervous system and contribute to long-term or cumulative effects that increase the risk of neurodegenerative conditions with age. This course will explore how environmental factors, from air pollution to pesticides, play a role in the pathogenesis of both neurodevelopmental and neurodegenerative conditions, as well as ongoing research into prevention and mitigation strategies. The first part of the course will discuss how perinatal exposure to environmental chemicals can disrupt normal neurodevelopment, emerging research tools in this area, and potential protective environmental factors, such as diet. The second half of the course will focus on the role of environmental exposures in the pathology of neurodegenerative conditions, including dementia and Parkinson’s disease.
Mitochondrial Toxicity and Parkinsonian Syndrome; Integrated Approach for Testing and Assessment (IATA)
Andrea Terron, DVM
Phytochemicals as Protectants Against Developmental Neurotoxicity from Chemical Exposure
Karen Litwa, PhD, East Carolina University Brody School of Medicine
Adverse Effects of Air Pollution on the Developing and Aging Brain
Pamela Lein, PhD, UC Davis
Developmental Origins of Cognitive Aging: Early Metals Exposure and Late Life Cognition
Marc Weisskopf, PhD, ScD, Harvard T.H. Chan School of Public Health