Animals were treated once daily with Compound X and lost body weight within the first few days and developed varying severity of hind-limb paresis and ataxia. What's Your Diagnosis?
Rats were administered Compound X or Compound Y daily by the oral gavage route for 10 days. Animals sacrificed on Day 5 and Day 10. What's Your Diagnosis?
Calves developed clinical signs of weakness, ataxia, depression, dehydration, diarrhea, and loss of appetite; Four died. A white powdery substance was found nearby. What's Your Diagnosis?
Groups of female rats, 10-11 weeks old, were exposed to a toxic vapor 6 hrs/day, 5 days/week for 6 weeks. The rats were then observed for 18 months after the end of exposure.
The photomicrographs are from rats with chronic, lifetime, whole body aerosol exposure to a test compound for 6 hours/day, 5 days/week, for 2 years.