2-year-old female Sprague Dawley rat

SIGNALMENT: (age, breed, sex, species, and scientific name) 
2-year-old female Sprague Dawley rat.

HISTORY: 
Rat in high-dose group on 2-year inhalation carcinogenicity study.   

GROSS PATHOLOGY:  
No relevant gross findings at necropsy.

LABORATORY RESULTS: (clinical pathology, microbiology, etc…)
N/A.

What's Your Diagnosis? Provide your possible etiologies in the comment section.

 

r101a.jpg

1X. H&E stain.  Section of posterior nasal cavity from rat on 2-year carcinogenicity study. 

r101b.jpg

4X. H&E stain.  Higher magnification of previous photomicrograph from section of posterior nasal cavity.

r101c.jpg

10X. H&E stain.  Higher magnification of previous photomicrograph from the posterior nasal cavity.

r101d.jpg

40X. H&E stain. Photomicrograph of malignant tumor in olfactory bulb region 

1 Comment

Olfactory Neuroblastoma (Carcinoma, Neuroepithelial)

November 25, 2019 04:18 PM by Pritpal Singh Malhi, BVSc, MVSc, PhD, DAVCP

Origin - Olfactory Epithelium

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