Male and female 35 and 70 day old Sprague Dawley rats

SIGNALMENT: (age, breed, sex, species, and scientific name) 
Male and female 35 and 70 day old Sprague Dawley rats.

TREATMENT PROTOCOL: (including test compound identification, dose, and class of molecule)
These rats were the offspring (F1) of a group of rats which were fed a compound from day 0 of pregnancy until weaning at 23 days of age. The compound was incorporated into their lab chow to deliver a dose of 15 mg / kg/ day. The rats were necropsied at 35 and 70 days of age.  

What's Your Diagnosis? Provide your possible etiologies in the comment section. 
Answers will be provided in September.

 

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70 day male 40x H&E 

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70 day female 40x H&E

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35 day male 20x H&E

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35 day female 40x H&E

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35 day female 10x H&E

 

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35 day female 40x H&E

 

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35 day female 5x H&E

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