Female F344/N rats, approximately 2 years old

SIGNALMENT: (age, breed, sex, species, and scientific name) 

Female F344/N rats, approximately 2 years old.

HISTORY:

The photomicrographs are from rats with chronic, lifetime, whole body aerosol exposure to a test compound for 6 hours/day, 5 days/week, for 2 years.

What's Your Diagnosis? Provide your possible etiologies in the comment section. 
Answers will be provided in March.

 

r140a.jpg

4X, H&E. Lung.


r140b.jpg

40X, H&E. Higher power view of alveoli. 


 
r140c.jpg

10X, H&E, Polarized light. Alveoli


 
r140d.jpg

2X, H&E. Lung


 
r140e.jpg

20X, H&E. Lung


 
r140f.jpg

2X, H&E. Lung


 
r140g.jpg

20X, H&E. Lung


 

 

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